SIRT6, a novel direct transcriptional target of FoxO3a, mediates colon cancer therapy

作者：Yingjie Zhang, Liming Nie, Keqian Xu, Yang Fu, Juchang Zhong, Kongzhen Gu, Lingling Zhang · 发表于：Theranostics · 年份：2019 · DOI：10.7150/thno.29724 · 被引用次数：73 · 研究领域：Sirtuins and Resveratrol in Medicine、PARP inhibition in cancer therapy、FOXO transcription factor regulation

: The results uncover SIRT6 as a new potential biomarker for colon cancer, and its unappreciated mechanism about transcription and expression via Akt/FoxO3a pathway.