Association of Maternal Cigarette Smoking and Smoking Cessation With Preterm Birth

作者：Samir Soneji, Hiram Beltrán‐Sánchez · 发表于：JAMA Network Open · 年份：2019 · DOI：10.1001/jamanetworkopen.2019.2514 · 被引用次数：169 · 研究领域：Smoking Behavior and Cessation、Gestational Diabetes Research and Management、Cancer Risks and Factors

Importance: Cigarette smoking during pregnancy increases the risk of preterm birth, low birth weight, and infant mortality. Objective: To assess the probability of preterm birth among expectant mothers who smoked cigarettes before pregnancy and quit smoking at the start or during pregnancy. Design, Setting, and Participants: This cross-sectional study analyzed information provided on live birth certificates from 2011 through 2017 that were obtained from US states that implemented the 2003 revision of the US live birth certificate. In total, 25 233 503 expectant mothers who delivered live neonates and had known prepregnancy and trimester-specific cigarette smoking frequency were included in the analyses. Exposures: Cigarette smoking frequency (1-9, 10-19, and ≥20 cigarettes per day) 3 months prior to pregnancy and for each trimester during pregnancy. Main Outcomes and Measures: Cigarette smoking cessation throughout pregnancy, after the first trimester, after the second trimester, and during the third trimester irrespective of first and second trimester smoking. Probability of preterm birth (<37 weeks' gestation). Results: Of 25 233 503 expectant mothers who delivered live neonates between 2011 and 2017, the modal age at delivery was 25 to 29 years; 52.9% were non-Hispanic white, 23.6% were Hispanic, and 14.2% were non-Hispanic black women; 22 600 196 mothers did not smoke during the 3 months prior to pregnancy, and 2 633 307 smoked during the 3 months prior to pregnancy. The ...