Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants

作者：Alexander Kutschera, Corinna Dawid, Nicolas Gisch, Christian Schmid, Lars Raasch, Tim Gerster, Milena Schäffer, Elwira Smakowska‐Luzan, Youssef Belkhadir, A. Corina Vlot, Courtney E. Chandler, Romain Schellenberger, Dominik Schwudke, Robert K. Ernst, Stéphan Dorey, Ralph Hückelhoven, Thomas Frank Hofmann, Stefanie Ranf · 发表于：Science · 年份：2019 · DOI：10.1126/science.aau1279 · 被引用次数：223 · 研究领域：Plant Pathogenic Bacteria Studies、Plant-Microbe Interactions and Immunity、Legume Nitrogen Fixing Symbiosis

A fatty acid triggers immune responses Plants and animals respond to the microbial communities around them, whether in antagonistic or mutualistic ways. Some of these interactions are mediated by lipopolysaccharide—a large, complex, and irregular molecule on the surface of most Gram-negative bacteria. Studying the small mustard plant Arabidopsis , Kutschera et al. identified a 3-hydroxydecanoyl chain as the structural element sensed by the plant's lectin receptor kinase. Indeed, synthetic 3-hydroxydecanoic acid alone was sufficient to produce a response. A small microbial metabolite may thus suffice to trigger immune responses. Science , this issue p. 178