Tobacco Smoking and Mortality in Asia

作者：Jae Jeong Yang, Danxia Yu, Wanqing Wen, Xiao‐Ou Shu, Eiko Saito, Md. Shafiur Rahman, Prakash C. Gupta, Jiang He, Shoichiro Tsugane, Yong-Bing Xiang, Yu-Tang Gao, Woon‐Puay Koh, Akiko Tamakoshi, Fujiko Irie, Atsuko Sadakane, Ichiro Tsuji, Seiki Kanemura, Keitaro Matsuo, Chisato Nagata, Chien‐Jen Chen, Jian‐Min Yuan, Myung‐Hee Shin, Sue K. Park, Wen‐Harn Pan, You‐Lin Qiao, Mangesh S. Pednekar, Dongfeng Gu, Norie Sawada, Hong-Lan Li, Jing Gao, Hui Cai, Eric J. Grant, Yasutake Tomata, Yumi Sugawara, Hidemi Ito, Keiko Wada, Chen‐Yang Shen, Renwei Wang, Yoon-Ok Ahn, San‐Lin You, Keun‐Young Yoo, Habibul Ashan, Kee Seng Chia, Paolo Boffetta, Manami Inoue, Daehee Kang, John D. Potter, Wei Zheng · 发表于：JAMA Network Open · 年份：2019 · DOI：10.1001/jamanetworkopen.2019.1474 · 被引用次数：179 · 研究领域：Smoking Behavior and Cessation、Health, Environment, Cognitive Aging、Birth, Development, and Health

Importance: Understanding birth cohort-specific tobacco smoking patterns and their association with total and cause-specific mortality is important for projecting future deaths due to tobacco smoking across Asian populations. Objectives: To assess secular trends of tobacco smoking by countries or regions and birth cohorts and evaluate the consequent mortality in Asian populations. Design, Setting, and Participants: This pooled meta-analysis was based on individual participant data from 20 prospective cohort studies participating in the Asia Cohort Consortium. Between September 1, 2017, and March 31, 2018, a total of 1 002 258 Asian individuals 35 years or older were analyzed using Cox proportional hazards regression analysis and random-effects meta-analysis. The pooled results were presented for mainland China; Japan; Korea, Singapore, and Taiwan; and India. Exposures: Tobacco use status, age at starting smoking, number of cigarettes smoked per day, and age at quitting smoking. Main Outcomes and Measures: Country or region and birth cohort-specific mortality and the population attributable risk for deaths from all causes and from lung cancer. Results: Of 1 002 258 participants (51.1% women and 48.9% men; mean [SD] age at baseline, 54.6 [10.4] years), 144 366 deaths (9158 deaths from lung cancer) were ascertained during a mean (SD) follow-up of 11.7 (5.3) years. Smoking prevalence for men steadily increased in China and India, whereas it plateaued in Japan and Korea, Singapore...