Anesthesia and surgery induce cognitive dysfunction in elderly male mice: the role of gut microbiota

作者：Gaofeng Zhan, Dongyu Hua, Niannian Huang, Yue Wang, Shan Li, Zhiqiang Zhou, Ning Yang, Riyue Jiang, Bin Zhu, Ling Yang, Yu Fan, Hui Xu, Chun Yang, Ailin Luo · 发表于：Aging · 年份：2019 · DOI：10.18632/aging.101871 · 被引用次数：71 · 研究领域：Intensive Care Unit Cognitive Disorders、Gut microbiota and health、Music Therapy and Health

genus are potentially important bacteria for the diagnosis of POCD. These findings indicate that alterations in the composition of gut microbiota are probably involved in the pathogenesis of POCD in aged mice. Novel therapeutic strategies regulating specific gut bacteria may be helpful for the prevention and treatment of POCD.