miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma

作者：Wen Cai Zhang, Julie Wells, Kin-Hoe Chow, He Huang, Min Yuan, Tanvi Saxena, Mary Ann Melnick, Katerina Politi, John M. Asara, Daniel B. Costa · 发表于：Nature Metabolism · 年份：2019 · DOI：10.1038/s42255-019-0052-9 · 研究领域：Cancer, Hypoxia, and Metabolism、RNA modifications and cancer、MicroRNA in disease regulation