[Electroacupuncture at "Zusanli" (ST36) and "Chize" (LU5) of mother rats exposed to nicotine during pregnancy and lactation has a protective effect on development of lung function and morphology in neonatal rats].

作者：Yunpeng Ge, Bo Ji, Guozhen Zhao, Yitian Liu, Hang Su, Jian Dai, Yawen Lu, Dan Wang, Reiko Sakurai, Virender K. Rehan, Ming-Na Yan, Xiaomin Sun, Hong-Xin Bai, Meng-Wei Guo, Xiao-Xuan Ren · 发表于：PubMed · 年份：2019 · DOI：10.13702/j.1000-0607.180438 · 被引用次数：3 · 研究领域：Acupuncture Treatment Research Studies、Andrographolide Research and Applications、Pediatric health and respiratory diseases

OBJECTIVE: To compare the different effect of electroacupuncture (EA) at "Zusanli" (ST36) and "Chize" (LU5) of mother rats exposed to Nicotine during pregnancy and lactation on lung function and morphological changes in offspring rats, so as to explore the most effective acupoint for improving the development of lung in neonatal rats. METHODS: day (childbirth day). The lung function of the offspring rats including the peak inspiratory flow (PIF), peak expiratory flow (PEF), lung resistance (RL), exhalation resistance (RE)and lung dynamic compliance (Cdyn) was detected by using a lung function analysis system. Histopathological changes (severity of alveolarization) of the offspring rats' lung tissue were observed under microscope after H．E. stain. RESULTS: >0.05)．. CONCLUSION: EA of ST36 and LU5 of mother rats experiencing nicotine exposure during pregnancy and lactation can improve the lung function and morphological changes in neonatal rats, and the effect of ST36 is relatively better.