[3 + 3]-Cycloaddition of α-Diazocarbonyl Compounds and N -Tosylaziridines: Synthesis of Polysubstituted 2 H -1,4-Oxazines through Synergetic Catalysis of AgOTf/Cu(OAc) 2

作者：Shangwen Fang, Yanwei Zhao, Haiyan Li, Yonggao Zheng, Pengcheng Lian, Xiaobing Wan · 发表于：Organic Letters · 年份：2019 · DOI：10.1021/acs.orglett.9b00632 · 被引用次数：23 · 研究领域：Cyclopropane Reaction Mechanisms、Synthesis and Catalytic Reactions、Catalytic C–H Functionalization Methods

An impressive and new [3 + 3]-cycloaddition of α-diazocarbonyl compounds with N -tosylaziridines via synergetic catalysis of AgOTf and Cu(OAc) 2 has been well described, which offers efficient access to highly substituted 2 H -1,4-oxazine derivatives. A variety of α-diazocarbonyl compounds and N -tosylaziridines were compatible substrates with convenient operations under mild reaction conditions.