Effects of home-based cardiac exercise rehabilitation with remote electrocardiogram monitoring in patients with chronic heart failure: a study protocol for a randomised controlled trial

作者：Jiahui Li, Peng Yang, Dongliang Fu, Xiaojun Ye, Lifang Zhang, Gang Chen, Yiyun Yang, He Luo, Li Chen, Mingjing Shao, Chunyan Li, Yi Liu, Ying Zhou, Hong Jiang, Xianlun Li · 发表于：BMJ Open · 年份：2019 · DOI：10.1136/bmjopen-2018-023923 · 被引用次数：25 · 研究领域：Cardiovascular and exercise physiology、Cardiac Health and Mental Health、Cardiovascular Effects of Exercise

Introduction Patients with chronic heart failure (CHF) can benefit from exercise rehabilitation (ER) with significant improvements in exercise capacity, quality of life and reduction in hospitalisations. Despite its reported benefits, only a small number of patients with CHF attend ER due to poor adherence, and improper exercise may even lead to adverse events. Remote ECG monitoring system (REMS) has the potential to overcome these obstacles. We hypothesise that home-based cardiac ER using REMS in CHF patients is effective compared with conventional ER without monitoring. Methods and analysis This study is a prospective, randomised, parallel controlled clinical trial designed to evaluate the effectiveness of home-based phase-II ER with REMS in the treatment of CHF with a target enrolment of 120 patients (left ventricular ejection fraction <50%, New York Heart Association (NYHA) classes I to III). Patients are randomised to either REMS rehabilitation group or conventional rehabilitation group in a 1:1 ratio. All patients start an exercise training in a supervised setting and then transition to a home-based regimen. The supervised training phase consists of 12 supervised training sessions, three sessions per week for 4 weeks. During the home exercise phase, patients exercise five times per week for 8 weeks. In the REMS group, patients wear monitors during exercise to ensure that exercise intensity is within the set ranges. REMS will also detect risky arrhythmia and alert the...