Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

作者：Catherine O. Johnson, Minh Nguyen, Gregory A. Roth, Emma Nichols, Shazia Alam, Degu Abate, Foad Abd-Allah, Ahmed Abdelalim, Haftom Niguse Abraha, Niveen ME Abu-Rmeileh, Oladimeji Adebayo, Abiodun M. Adeoye, Gina Agarwal, Sutapa Agrawal, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Fares Alahdab, Raghib Ali, Nelson Alvis‐Guzmán, Nahla Anber, Mina Anjomshoa, Jalal Arabloo, Antonio Araúz, Johan Ärnlöv, Amit Arora, Ashish Awasthi, Maciej Banach, Miguel A. Barboza, Suzanne Barker‐Collo, Till Bärnighausen, Sanjay Basu, Abate Bekele Belachew, Yaschilal Muche Belayneh, Derrick Bennett, Isabela M. Benseñor, Krittika Bhattacharyya, Belete Biadgo, Ali Bijani, Boris Bikbov, Muhammad Shahdaat Bin Sayeed, Zahid A Butt, Lucero Cahuana-Hurtado, Juan Jesús Carrero, Félix Carvalho, Carlos A Castañeda-Orjuela, Franz Castro, Ferrán Catalá-López, Yazan Chaiah, Peggy Pei-Chia Chiang, Jee-Young J Choi, Hanne Christensen, Dinh‐Toi Chu, Monica Cortinovis, Albertino Damasceno, Lalit Dandona, Rakhi Dandona, Ahmad Daryani, Kairat Davletov, Barbora de Courten, Vanessa De la Cruz‐Góngora, Meaza Girma Degefa, Samath Dhamminda Dharmaratne, Daniel Díaz, Manisha Dubey, Eyasu Ejeta Duken, Dumessa Edessa, Matthias Endres, Emerito Jose A Faraon, Farshad Farzadfar, Eduarda Fernandes, Florian Fischer, Luísa Sório Flor, Morsaleh Ganji, Abadi Kahsu Gebre, Teklu Gebrehiwo Gebremichael, Birhanu Geta, Kebede Embaye Gezae, Paramjit Gill, E. V. Gnedovskaya, Hector Gómez‐Dantés, Alessandra C. Goulart, Giuseppe Grosso, Yuming Guo, Rajeev Gupta, Arvin Haj‐Mirzaian, Arya Haj‐Mirzaian, Samer Hamidi, Graeme J. Hankey, Hamid Yimam Hassen, Simon I Hay, Mohamed Hegazy, Behnam Heidari, Nabeel Herial, Mohammad Ali Hosseini, Sorin Hostiuc, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam, Nader Jahanmehr, Mehdi Javanbakht, Ravi Prakash Jha, Jost B. Jonas, Jacek Jerzy Jozwiak, Mikk Jürisson, Amaha Kahsay, Rizwan Kalani, Yogeshwar Kalkonde, Teshome Abegaz Kamil, Tanuj Kanchan, André Karch, Narges Karimi, Hamidreza Karimi‐Sari, Amir Kasaeian, Tesfaye Kassa, Hossein Kazemeini, Adane Teshome Kefale, Yousef Khader, Ibrahim A. Khalil, Ejaz Ahmad Khan, Young‐Ho Khang, Jagdish Khubchandani, Daniel Kim, Yun Jin Kim, Adnan Kısa, Mika Kivimäki, Ai Koyanagi, Rita Krishnamurthi, G Anil Kumar, Alessandra Lafranconi, Sarah Lewington, Shanshan Li, Warren Lo, Alan D Lopez, Stefan Lorkowski, Paulo A. Lotufo, Mark T. Mackay, Marek Majdán, Reza Majdzadeh, Azeem Majeed, Reza Malekzadeh, Navid Manafi, Mohammad Alì Mansournia, Man Mohan Mehndiratta, Varshil Mehta, Getnet Mengistu, Atte Meretoja, Tuomo J Meretoja, Bartosz Miazgowski, Tomasz Miazgowski, Ted R. Miller, Erkin М Мirrakhimov, Bahram Mohajer, Yousef Mohammad, Milad Khorasani, Shafiu Mohammed, Farnam Mohebi, Ali H. Mokdad, Yaser Mokhayeri, Ghobad Moradi, Lídia Morawska, Ilais Moreno Velásquez, Seyyed Meysam Mousavi, Oumer Sada Muhammed, Walter Muruet-Gutierrez, Mehdi Naderi, Mohsen Naghavi, Gurudatta Naik, Bruno Ramos Nascimento, Ruxandra Irina Negoi, Cuong Tat Nguyen, Long Hoang Nguyen, Yirga Legesse Nirayo, Bo Norrving, Jean Jacques Noubiap, Richard Ofori‐Asenso, Felix Akpojene Ogbo, Andrew T Olagunju, Tinuke O Olagunju, Mayowa Owolabi, Jeyaraj Pandian, Shanti Patel, Norberto Perico, М. А. Пирадов, Suzanne Polinder, Maarten J. Postma, Hossein Poustchi, V. Prakash, Mostafa Qorbani, Alireza Rafiei, Fakher Rahim, Kazem Rahimi, Vafa Rahimi‐Movaghar, Mahfuzar Rahman, Muhammad Aziz Rahman, Cesar Reis, Giuseppe Remuzzi, André M. N. Renzaho, Stefano Ricci, Nicholas L S Roberts, Stephen R. Robinson, Leonardo Roever, Gholamreza Roshandel, Parisa Sabbagh, Hosein Safari, Saeed Safari, Saeid Safiri, Amirhossein Sahebkar, Saleh Salehi Zahabi, Abdallah M Samy, Paola Santalucia, Itamar S Santos, João Vasco Santos, Milena M Santric-Milicevic, Benn Sartorius, Arundhati R Sawant, Aletta E. Schutte, Sadaf G Sepanlou, Azadeh Shafieesabet, Masood Ali Shaikh, Mehran Shams-Beyranvand, Aziz Sheikh, Kevin N. Sheth, Kenji Shibuya, Mika Shigematsu, Min‐Jeong Shin, Ivy Shiue, Soraya Siabani, Badr Hasan Sobaih, Luciano A. Sposato, Ipsita Sutradhar, PN Sylaja, Cassandra Szoeke, Braden Te Ao, Mohamad‐Hani Temsah, Omar Temsah, Amanda G. Thrift, Marcello Tonelli, Roman Topór-Mądry, Bach Xuan Tran, Khanh Bao Tran, Thomas Clement Truelsen, Afewerki Gebremeskel Tsadik, Irfan Ullah, Olalekan A. Uthman, Muthiah Vaduganathan, Pascual Valdéz, Tommi Vasankari, Vasanthan Rajagopalan, Narayanaswamy Venketasubramanian, Kia Vosoughi, Giang Thu Vu, Yasir Waheed, Elisabete Weiderpass, Kidu Gidey Weldegwergs, Ronny Westerman, Charles Wolfe, Dawit Zewdu Wondafrash, Gelin Xu, Ali Yadollahpour, Tomohide Yamada, Hiroshi Yatsuya, Ebrahim M Yimer, Naohiro Yonemoto, Mahmoud Yousefifard, Chuanhua Yu, Zoubida Zaidi, Mohammad Zamani, Afshin Zarghi, Yunquan Zhang, Sanjay Zodpey, Valery L. Feigin, Theo Vos, Christopher J L Murray · 发表于：The Lancet Neurology · 年份：2019 · DOI：10.1016/s1474-4422(19)30034-1 · 被引用次数：3400 · 研究领域：Acute Ischemic Stroke Management、Frailty in Older Adults、Stroke Rehabilitation and Recovery

BACKGROUND: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. METHODS: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, prevalence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs). DALYs were generated by summing YLLs and YLDs. Cause-specific mortality was estimated using an ensemble modelling process with vital registration and verbal autopsy data as inputs. Non-fatal estimates were generated using Bayesian meta-regression incorporating data from registries, scientific literature, administrative records, and surveys. The Socio-demographic Index (SDI), a summary indicator generated using educational attainment, lagged distributed income, and total fertility rate, was used to group countries into quintiles. FINDINGS: In 2016, there were 5·5 million (95% UI 5·3 to 5·7) deaths and 116·4 million (111·4 to 121·4) DALYs due to stroke. The global age-stand...