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Comparative Analysis of bla KPC Expression in Tn 4401 Transposons and the Tn 3 -Tn 4401 Chimera

作者:Jiansheng Huang, Xiaolei Hu, Yunan Zhao, Yang Shi, Hui Ding, Rongzhen Wu, Zhigang Zhao, Jiansong Ji · 发表于:Antimicrobial Agents and Chemotherapy · 年份:2019 · DOI:10.1128/aac.02434-18 · 被引用次数:24 · 研究领域:Antibiotic Resistance in Bacteria、Antibiotics Pharmacokinetics and Efficacy、Bacterial Identification and Susceptibility Testing

Two basic structures that carry the bla KPC gene, the Tn 4401 transposon and the Tn 3 -Tn 4401 chimera, have been identified within and outside China. However, the different bla KPC expression levels and promoter activities of these two structures are not completely understood.