Effects of Absolute Humidity, Relative Humidity, Temperature, and Wind Speed on Influenza Activity in Toronto, Ontario, Canada

作者：Adriana Peci, Anne‐Luise Winter, Li Ye, Saravanamuttu Gnaneshan, Juan Liu, Samira Mubareka, Jonathan B. Gubbay · 发表于：Applied and Environmental Microbiology · 年份：2019 · DOI：10.1128/aem.02426-18 · 被引用次数：140 · 研究领域：Influenza Virus Research Studies、Respiratory viral infections research、COVID-19 epidemiological studies

This study examined the relationship between environmental factors and the occurrence of influenza in general. Since the seasonality of influenza A and B viruses is different in most temperate climates, we also examined each influenza virus separately. This study reports a negative association of both absolute humidity and temperature with influenza A and B viruses and tries to understand the controversial effect of RH on influenza A and B viruses. This study reports a nonlinear relation between influenza A and B viruses with temperature and influenza B virus with absolute and relative humidity. The nonlinear nature of these relations could explain the complexity and difference in seasonality between influenza A and B viruses, with the latter predominating later in the season. Separating community-based specimens from those obtained during outbreaks was also a novel approach in this research. These findings provide a further understanding of influenza virus transmission in temperate climates.