Establishing a perinatal red blood cell transfusion risk evaluation model for obstetric patients: a retrospective cohort study

作者：Zhun Xing, Yanjing He, Chao Ji, Chang Xu, Wen Zhang, Yunhui Li, Xiangqian Tan, Ping Zhao, Qiushi Wang, Liqiang Zheng · 发表于：Transfusion · 年份：2019 · DOI：10.1111/trf.15208 · 被引用次数：12 · 研究领域：Maternal and fetal healthcare、Blood transfusion and management、Trauma, Hemostasis, Coagulopathy, Resuscitation

BACKGROUND: The ability to predict risk factors for blood transfusion after postpartum hemorrhage could enhance the performance of lifesaving procedures in patients who experience postpartum hemorrhage. Therefore, this study aimed to evaluate these risk factors and create a scoring system for blood transfusion evaluations and risk in obstetric patients. STUDY DESIGN AND METHODS: Diagnosis and blood transfusion data of 14,112 women who delivered between January 1, 2015, and December 31, 2015, were analyzed. A binary logistic regression model was used. We conducted univariate analyses of each risk factor as well as multivariable logistic regression analysis. Data of obstetric patients in 2016 validated the receiver operating characteristic curve. A risk prediction score was generated from the transfusion risk factor β-coefficients in the multivariable logistic regression model. RESULTS: In total, 392 (2.94%) of 13,328 patients received transfusions. After multivariable adjustment, polyembryony, anemia, thrombocytopenia, preeclampsia, placenta previa, placental implantation, uterine scarring, uterine rupture, retained placenta, stillbirth, and HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) were significantly associated with perinatal transfusion. Heart disease and hemophilia were not related to transfusion risk. The blood transfusion risk evaluation table was well calibrated. CONCLUSIONS: Our retrospective analysis revealed that diagnoses including polyemb...