CircHMGCS1 Promotes Hepatoblastoma Cell Proliferation by Regulating the IGF Signaling Pathway and Glutaminolysis

作者：Ni Zhen, Song Gu, Ji Ma, Jiabei Zhu, Minzhi Yin, Min Xu, Jing Wang, Nan Huang, Zhongqi Cui, Zhixuan Bian, Fenyong Sun, Qiuhui Pan · 发表于：Theranostics · 年份：2019 · DOI：10.7150/thno.29515 · 被引用次数：116 · 研究领域：Circular RNAs in diseases、Cancer-related molecular mechanisms research、MicroRNA in disease regulation

The circHMGCS1/miR-503-5p/IGF-PI3K-Akt axis regulates the proliferation, apoptosis and glutaminolysis of HB cells, implying that circHMGCS1 is a promising therapeutic target and prognostic marker for HB patients.