Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

作者：Brian C. Miller, Debattama R. Sen, Rose Al Abosy, Kevin Bi, Yamini V. Virkud, Martin W. LaFleur, Kathleen B. Yates, Ana Lako, Kristen D. Felt, Girish S. Naik, Michael P. Manos, Evisa Gjini, Juhi R. Kuchroo, Jeffrey J. Ishizuka, Jenna L. Collier, Gabriel K. Griffin, Seth Maleri, Dawn E. Comstock, Sarah A. Weiss, Flavian D. Brown, Arpit Panda, Margaret D. Zimmer, Robert T. Manguso, F. Stephen Hodi, Scott J. Rodig, Arlene H. Sharpe, W. Nicholas Haining · 发表于：Nature Immunology · 年份：2019 · DOI：10.1038/s41590-019-0312-6 · 被引用次数：2157 · 研究领域：Cancer Immunotherapy and Biomarkers、CAR-T cell therapy research、Immune Cell Function and Interaction