Photoelectrochemical C−H Alkylation of Heteroarenes with Organotrifluoroborates

作者：Hong Yan, Zhong‐Wei Hou, Hai‐Chao Xu · 发表于：Angewandte Chemie International Edition · 年份：2019 · DOI：10.1002/anie.201814488 · 被引用次数：287 · 研究领域：Radical Photochemical Reactions、Sulfur-Based Synthesis Techniques、CO2 Reduction Techniques and Catalysts

A photoelectrochemical method for the C-H alkylation of heteroarenes with organotrifluoroborates has been developed. The merger of electrocatalysis and photoredox catalysis provides a chemical oxidant-free approach for the generation and functionalization of alkyl radicals from organotrifluoroborates. A variety of heteroarenes were functionalized using primary, secondary, and tertiary alkyltrifluoroborates with excellent regio- and chemoselectivity.