Combined 5‐minute double‐echo in steady‐state with separated echoes and 2‐minute proton‐density‐weighted 2D FSE sequence for comprehensive whole‐joint knee MRI assessment

作者：Akshay Chaudhari, Kathryn J. Stevens, Bragi Sveinsson, Jeff Wood, Christopher F. Beaulieu, Edwin H. G. Oei, Jarrett Rosenberg, Feliks Kogan, Marcus T. Alley, Garry E. Gold, Brian A. Hargreaves · 发表于：Journal of Magnetic Resonance Imaging · 年份：2018 · DOI：10.1002/jmri.26582 · 被引用次数：38 · 研究领域：Osteoarthritis Treatment and Mechanisms、Knee injuries and reconstruction techniques、Lower Extremity Biomechanics and Pathologies

BACKGROUND: Clinical knee MRI protocols require upwards of 15 minutes of scan time. PURPOSE/HYPOTHESIS: To compare the imaging appearance of knee abnormalities depicted with a 5-minute 3D double-echo in steady-state (DESS) sequence with separate echo images, with that of a routine clinical knee MRI protocol. A secondary goal was to compare the imaging appearance of knee abnormalities depicted with 5-minute DESS paired with a 2-minute coronal proton-density fat-saturated (PDFS) sequence. STUDY TYPE: Prospective. SUBJECTS: Thirty-six consecutive patients (19 male) referred for a routine knee MRI. FIELD STRENGTH/SEQUENCES: DESS and PDFS at 3T. ASSESSMENT: Five musculoskeletal radiologists evaluated all images for the presence of internal knee derangement using DESS, DESS+PDFS, and the conventional imaging protocol, and their associated diagnostic confidence of the reading. STATISTICAL TESTS: Differences in positive and negative percent agreement (PPA and NPA, respectively) and 95% confidence intervals (CIs) for DESS and DESS+PDFS compared with the conventional protocol were calculated and tested using exact McNemar tests. The percentage of observations where DESS or DESS+PDFS had equivalent confidence ratings to DESS+Conv were tested with exact symmetry tests. Interreader agreement was calculated using Krippendorff's alpha. RESULTS: DESS had a PPA of 90% (88-92% CI) and NPA of 99% (99-99% CI). DESS+PDFS had increased PPA of 99% (95-99% CI) and NPA of 100% (99-100% CI) compared w...