Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

作者：Derin B. Keskin, Annabelle J. Anandappa, Jing Sun, Itay Tirosh, Nathan D. Mathewson, Shuqiang Li, Giacomo Oliveira, Anita Giobbie‐Hurder, Kristen D. Felt, Evisa Gjini, Sachet Ashok Shukla, Zhuting Hu, Letitia Li, Phuong M. Le, Rosa Lundbye Allesøe, Alyssa R. Richman, Monika S. Kowalczyk, Sara Abdelrahman, Jack E. Geduldig, Sarah K. Charbonneau, Kristine Pelton, Julian Bryan Iorgulescu, Liudmila Elagina, Wandi Zhang, Oriol Olive, Christine Sceppa McCluskey, Lars Rønn Olsen, Jonathan D. Stevens, William J. Lane, Andres Μ. Salazar, Heather Daley, Patrick Yung Wen, Ennio Antonio Chiocca, Maegan V. Harden, Niall J. Lennon, Stacey L. Gabriel, Gad A. Getz, Eric S. Lander, Aviv Regev, Jerome Ritz, Donna S Neuberg, Scott J. Rodig, Keith Lloyd Ligon, Mario L. Suvà, Kai W. Wucherpfennig, Nir Hacohen, Edward F. Fritsch, Kenneth J. Livak, Patrick Alexander Ott, Catherine J. Wu, David A. Reardon · 发表于：Nature · 年份：2018 · DOI：10.1038/s41586-018-0792-9 · 被引用次数：1482 · 研究领域：Immunotherapy and Immune Responses、Cancer Immunotherapy and Biomarkers、CAR-T cell therapy research