Flavonoids: biological activities and therapeutic potential

作者：Mércia Marques Jucá, Francisco Maurício Sales Cysne Filho, Jamily Cunha de Almeida, Dara da Silva Mesquita, Jéssica Rodrigues de Moraes Barriga, Kátia Cilene Ferreira Dias, Talita Matias Barbosa, Luna Costa Vasconcelos, Luzia Kalyne Almeida Moreira Leal, José Eduardo Ribeiro, Silvânia Maria Mendes Vasconcelos · 发表于：Natural Product Research · 年份：2018 · DOI：10.1080/14786419.2018.1493588 · 被引用次数：463 · 研究领域：Phytochemicals and Antioxidant Activities、Natural Antidiabetic Agents Studies、Bee Products Chemical Analysis

Flavonoids have aroused much interest in research, since they present a great diversity of biological activities observed in vitro, such as: antioxidant effect, modulation of the enzymatic activity and inhibition of cellular proliferation, exerting beneficial effects on the organism, as well as the use of its therapeutic potential. With wide distribution in the plant kingdom represent a class of phenolic compounds that differ in their chemical structure and particular characteristics. The objective of this review was to describe the relevant aspects of flavonoids, reporting the different known groups, the probable mechanisms by which they act, their pharmacological properties and to gain a better understanding of the reported beneficial health effects of these substances. This systematic review consisted of research using scientific databases such as Scopus, Science Direct, PubMed, SciVerse and SciELO, without time limitation. Some pharmacological properties of some flavonoids and their health benefits have been confirmed by previous studies.