Saccharomyces cerevisiae fungemia in a critically ill patient with acute cholangitis and long term probiotic use

作者：Mustafa Fadhel, Swapnil Patel, Edward Liu, Michael D. Levitt, Arif Asif · 发表于：Medical Mycology Case Reports · 年份：2018 · DOI：10.1016/j.mmcr.2018.11.003 · 被引用次数：45 · 研究领域：Probiotics and Fermented Foods、Antifungal resistance and susceptibility、Microbial Metabolites in Food Biotechnology

Saccharomyces cerevisiae has recently been used as an ingredient in probiotic supplements. Invasive Saccharomyces infection have been documented, and multiple predisposing risk factors have been identified including critical illness, ICU admission, antibiotics use, central venous catheters, probiotics use, and immunosuppression. We report a case of a 74-year-old man admitted for acute cholangitis taking a probiotic supplement containing the subtype Saccharomyces boulardii. He later developed S. cerevisiae fungemia that was successfully treated with Micafungin and Fluconazole.