Design of amidobenzimidazole STING receptor agonists with systemic activity

作者：Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang, N.O. Concha, Robert R. Singhaus, Shuyun Zhang, Jean-Luc Tran, Patrick Moore, Stephanie Lehmann, H. Christian Eberl, Marcel Muelbaier, Jessica L. Schneck, Jim Clemens, Michael Adam, John F. Mehlmann, Joseph J. Romano, Angel Morales, James Kang, Lara K. Leister, Todd L. Graybill, Adam K. Charnley, Guosen Ye, Neysa Nevins, Kamelia Behnia, Amaya I. Wolf, Viera Kasparcova, Kelvin Nurse, Liping Wang, Ana C. Puhl, Yue Li, Michael Klein, Christopher B. Hopson, Jeffrey Guss, Marcus Bantscheff, Giovanna Bergamini, Michael Reilly, Yiqian Lian, Kevin J. Duffy, Jerry L. Adams, Kevin P. Foley, Peter J. Gough, Robert W. Marquis, James Smothers, Axel Hoos, John Bertin · 发表于：Nature · 年份：2018 · DOI：10.1038/s41586-018-0705-y · 被引用次数：892 · 研究领域：interferon and immune responses、Inflammasome and immune disorders、Immune Response and Inflammation