BRI1 controls vascular cell fate in the Arabidopsis root through RLP44 and phytosulfokine signaling

作者：Eleonore Holzwart, Apolonio Ignacio Huerta, Nina Glöckner, Borja Garnelo Gómez, Friederike Wanke, Sebastian Augustin, Jana Christin Askani, Ann-Kathrin Schürholz, Klaus Harter, Sebastian Wolf · 发表于：Proceedings of the National Academy of Sciences · 年份：2018 · DOI：10.1073/pnas.1814434115 · 被引用次数：104 · 研究领域：Plant Molecular Biology Research、Plant Reproductive Biology、Photosynthetic Processes and Mechanisms

Significance Cell-fate determination and cellular behavior in plants rely mainly on positional information and intercellular communication. A plethora of cues are perceived by surface receptors and integrated into an adequate cellular output. Here, we show that the small receptor-like protein RLP44 acts as an intermediary to connect the receptors for two well-known signaling molecules, brassinosteroid and phytosulfokine, to control cell fate in the root vasculature. Furthermore, we show that the brassinosteroid receptor has functions that are independent from the responses to its hormone ligands and reveal that phytosulfokine signaling promotes procambial cell identity. These results provide a mechanistic framework for the integration of multiple signaling pathways at the plasma membrane by shifting associations of receptors in multiprotein complexes.