Efficacy and safety for apatinib combined with oxaliplatin and S1 in initially treated metastatic gastric cancer: A single-center observational study

作者：Peng Jj, Liang Peng, Hongxun Wu, Ketong Wu, Wei Chen, Chenxi Xie, Jianmin Xu, Xiaoer Zhang, Dongying Chen, Shirong Cai, Yulong He · 发表于：Annals of Oncology · 年份：2018 · DOI：10.1093/annonc/mdy282.060 · 研究领域：Gastric Cancer Management and Outcomes、Cholangiocarcinoma and Gallbladder Cancer Studies、Colorectal Cancer Treatments and Studies

Background: Currently, S-1 combined with oxaliplatin (SOX) is widely used in the first-line treatment of advanced gastric cancer in China. Apatinib has demonstrated encouraging anti-cancer activity in gastric cancer within both in vitro and in vivo models. We evaluated the efficacy and safety of apatinib combined with SOX in initially treated patients with metastatic gastric cancer.