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Total synthesis of (−)-8- epi -chromazonarol enabled by a unique N 2 H 4 ·H 2 O promoted intramolecular oxa-Michael cyclization reaction

作者:Lin Liu, Huayue Song, Peng Chen, Ziyun Yuan, Shangbiao Feng, Weiwei Zhang, Bowen Fang, Xingang Xie, Xuegong She · 发表于:Organic Chemistry Frontiers · 年份:2018 · DOI:10.1039/c8qo00901e · 被引用次数:13 · 研究领域:Chemical synthesis and alkaloids、Synthetic Organic Chemistry Methods、Axial and Atropisomeric Chirality Synthesis

The first enantioselective synthesis of 8- epi -chromazonarol was achieved by a N 2 H 4 ·H 2 O promoted highly diastereoselective oxa-Michael cyclization reaction.