[3 + 2] Cycloaddition of Nitrile Ylides with Diazonium Salts: Copper-Catalyzed One-Pot Synthesis of Fully Substituted 1,2,4-Triazoles

作者：Huihuang Li, Xueli Wu, Weiwei Hao, Haiyan Li, Yanwei Zhao, Yaxiong Wang, Pengcheng Lian, Yonggao Zheng, Xiaoguang Bao, Xiaobing Wan · 发表于：Organic Letters · 年份：2018 · DOI：10.1021/acs.orglett.8b02172 · 被引用次数：45 · 研究领域：Cyclopropane Reaction Mechanisms、Catalytic C–H Functionalization Methods、Catalytic Alkyne Reactions

A novel [3 + 2] cycloaddition between nitrile ylides and diazonium salts was well-established. This copper-catalyzed three-component reaction was distinguished by mild conditions, ready availability, and operational simplicity, thus opening access to 1,2,4-triazoles with a diverse set of substitution patterns.