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Finding useful biomarkers for Parkinson’s disease

作者:Alice S. Chen‐Plotkin, Roger L. Albin, Roy N. Alcalay, Debra Babcock, Vikram S. Bajaj, Dubois Bowman, ALEX M. BUKO, Jesse M. Cedarbaum, Daniel Chelsky, Mark Cookson, Ted M. Dawson, Richard B. Dewey, Tatiana Foroud, Mark A. Frasier, Dwight C. German, Katrina Gwinn, Xuemei Huang, Catherine Kopil, Thomas Leon Kremer, Shirley Lasch, KENNETH L. MAREK, Jarrod A. Marto, Kalpana Merchant, Brit Mollenhauer, Anna Naito, Judith A. Potashkin, Alyssa N. Reimer, Liana S. Rosenthal, Rachel Saunders‐Pullman, Clemens R. Scherzer, Todd Sherer, Andrew B. Singleton, Margaret L. Sutherland, Ines Thiele, Marcel van der Brug, Kendall R. Van Keuren‐Jensen, David E. Vaillancourt, David R. Walt, Andrew B. West, Jing Zhang · 发表于:Science Translational Medicine · 年份:2018 · DOI:10.1126/scitranslmed.aam6003 · 被引用次数:153 · 研究领域:Parkinson's Disease Mechanisms and Treatments、Nuclear Receptors and Signaling、Biotin and Related Studies

The recent advent of an "ecosystem" of shared biofluid sample biorepositories and data sets will focus biomarker efforts in Parkinson's disease, boosting the therapeutic development pipeline and enabling translation with real-world impact.