Amine–carboxylate supramolecular synthon in pharmaceutical cocrystals

作者：Duanxiu Li, Minmin Kong, Jiang Li, Zongwu Deng, Hailu Zhang · 发表于：CrystEngComm · 年份：2018 · DOI：10.1039/c8ce01106k · 被引用次数：31 · 研究领域：Crystallography and molecular interactions、Crystallization and Solubility Studies、Energetic Materials and Combustion

Four novel pharmaceutical cocrystals of l -proline were obtained via combined virtual and experimental screening. The results confirm that an amine–carboxylate supramolecular synthon can be used for pharmaceutical cocrystal design.