The association between body mass index, waist circumference, waist–hip ratio and cognitive disorder in older adults

作者：Zhizhen Liu, Hongqing Yang, Shiya Chen, Jing Cai, Zijie Huang · 发表于：Journal of Public Health · 年份：2018 · DOI：10.1093/pubmed/fdy121 · 被引用次数：81 · 研究领域：Dementia and Cognitive Impairment Research、Nutrition and Health in Aging、Bariatric Surgery and Outcomes

PURPOSE: To examine the association between body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR) and cognitive disorder in older adults. METHODS: Cross-sectional data from the mini-mental state examination questionnaire and physical examination of older adults (≥65, n = 1037) were collected and analyzed. Logistic regression examined the odds ratios (ORs) of cognitive performance according to BMI, WC and WHR. RESULTS: The prevalence of cognitive dysfunction in older adults was 13.0%. The BMI-based overweight rate, obesity rate and central obesity rate calculated by either WC or WHR were 39.6, 11.4% and 66.5, 65.6%, respectively. The risk of cognitive impairment was increased in elderly individuals ≥70 years old than in those <70 years old (OR = 1.738). In addition, gender, WHR and smoking habit were also significantly different between the two age groups (P < 0.05). We examined the effects of different BMI values and WC/WHR central obesity on cognition impairment in ≥70-year-old adults and found that BMI obesity and WC/WHR central obesity had a combined effect on the incidence of cognition impairment (OR = 3.076 and OR = 3.584). CONCLUSIONS: BMI obesity and WC/WHR central obesity have a combined effect on cognitive impairment and WHR has a stronger association with cognitive impairment than WC.