An enhanced CRISPR repressor for targeted mammalian gene regulation

作者：Nan Cher Yeo, Alejandro Chavez, Alissa Lance‐Byrne, Yingleong Chan, David J Menn, Denitsa Milanova, Chih-Chung Kuo, Xiaoge Guo, Sumana Sharma, Angela Tung, Ryan J. Cecchi, Marcelle Tuttle, Swechchha Pradhan, Elaine T. Lim, Noah Davidsohn, Mo R. Ebrahimkhani, James J. Collins, Nathan E. Lewis, Samira Kiani, George M. Church · 发表于：Nature Methods · 年份：2018 · DOI：10.1038/s41592-018-0048-5 · 被引用次数：538 · 研究领域：CRISPR and Genetic Engineering、RNA and protein synthesis mechanisms、Advanced biosensing and bioanalysis techniques