Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies

作者：Meng Lei, Huayun Feng, Enhe Bai, Hui Zhou, Jia Wang, Jingmiao Shi, Xueyuan Wang, Shihe Hu, Zhaogang Liu, Yongqiang Zhu · 发表于：Bioorganic & Medicinal Chemistry · 年份：2018 · DOI：10.1016/j.bmc.2018.06.020 · 被引用次数：12 · 研究领域：Peptidase Inhibition and Analysis、Multiple Myeloma Research and Treatments、Ubiquitin and proteasome pathways