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Multi-omics approaches confirm metal ions mediate the main toxicological pathways of metal-bearing nanoparticles in lung epithelial A549 cells

作者:Susan Dekkers, Tim Williams, Jinkang Zhang, Jiarui Zhou, Rob J. Vandebriel, Liset J.J. de la Fonteyne, Eric R. Gremmer, Shan He, Emily J. Guggenheim, Iseult Lynch, Flemming R. Cassee, Wim H. de Jong, Mark R. Viant · 发表于:Environmental Science Nano · 年份:2018 · DOI:10.1039/c8en00071a · 被引用次数:46 · 研究领域:Nanoparticles: synthesis and applications、Heavy Metal Exposure and Toxicity、Healthcare and Environmental Waste Management

Our analyses confirm that the dissolution of metal ions mediates the main toxicological pathways of silver and zinc oxide nanoparticles.