Volatiles from three genome sequenced fungi from the genus Aspergillus

作者：Jeroen S. Dickschat, Ersin Celik, Nelson L. Brock · 发表于：Beilstein Journal of Organic Chemistry · 年份：2018 · DOI：10.3762/bjoc.14.77 · 被引用次数：14 · 研究领域：Essential Oils and Antimicrobial Activity、Advanced Chemical Sensor Technologies、Microbial Natural Products and Biosynthesis

The volatiles emitted by agar plate cultures of three genome sequenced fungal strains from the genus Aspergillus were analysed by GC–MS. All three strains produced terpenes for which a biosynthetic relationship is discussed. The obtained data were also correlated to genetic information about the encoded terpene synthases for each strain. Besides terpenes, a series of aromatic compounds and volatiles derived from fatty acid and branched amino acid metabolism were identified. Some of these compounds have not been described as fungal metabolites before. For the compound ethyl ( E )-hept-4-enoate known from cantaloupe a structural revision to the Z stereoisomer is proposed. Ethyl ( Z )-hept-4-enoate also occurs in Aspergillus clavatus and was identified by synthesis of an authentic standard.