Electrochemical dehydrogenative cyclization of 1,3-dicarbonyl compounds

作者：Zheng‐Jian Wu, Shi‐Rui Li, Hao Long, Hai‐Chao Xu · 发表于：Chemical Communications · 年份：2018 · DOI：10.1039/c8cc02472c · 被引用次数：107 · 研究领域：Radical Photochemical Reactions、Catalytic C–H Functionalization Methods、Oxidative Organic Chemistry Reactions

The intramolecular C(sp3)-H/C(sp2)-H cross-coupling of 1,3-dicarbonyl compounds has been achieved through Cp2Fe-catalyzed electrochemical oxidation. The key to the success of these dehydrogenative cyclization reactions is the selective activation of the acidic α-C-H bond of the 1,3-dicarbonyl moiety to generate a carbon-centered radical.