Nipah Virus Infection

作者：Brenda Ang, C. C. Tchoyoson Lim, Lin‐Fa Wang · 发表于：Journal of Clinical Microbiology · 年份：2018 · DOI：10.1128/jcm.01875-17 · 被引用次数：299 · 研究领域：Virology and Viral Diseases、Viral Infections and Vectors、Rabies epidemiology and control

Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.