ONC201 kills breast cancer cells in vitro by targeting mitochondria

作者：Yoshimi Endo Greer, Natalie Porat‐Shliom, Kunio Nagashima, Christina H. Stuelten, Dan Crooks, Vishal N. Kopardé, Samuel F. Gilbert, Celia Islam, Ashley Ubaldini, Yun Ji, Luca Gattinoni, Ferri Soheilian, Xiantao Wang, Markus Hafner, Jyoti Shetty, Bao Tran, Parthav Jailwala, Maggie Cam, Martin Lang, Donna Voeller, William C. Reinhold, Vinodh N. Rajapakse, Yves Pommier, Roberto Weigert, W. Marston Linehan, Stanley Lipkowitz · 发表于：Oncotarget · 年份：2018 · DOI：10.18632/oncotarget.24862 · 被引用次数：99 · 研究领域：Mitochondrial Function and Pathology、ATP Synthase and ATPases Research、Cell death mechanisms and regulation

// Yoshimi Endo Greer 1 , Natalie Porat-Shliom 2 , Kunio Nagashima 3 , Christina Stuelten 2 , Dan Crooks 4 , Vishal N. Koparde 5 , Samuel F. Gilbert 1 , Celia Islam 1 , Ashley Ubaldini 1 , Yun Ji 6 , Luca Gattinoni 6 , Ferri Soheilian 3 , Xiantao Wang 7 , Markus Hafner 7 , Jyoti Shetty 8 , Bao Tran 8 , Parthav Jailwala 5 , Maggie Cam 5 , Martin Lang 4 , Donna Voeller 1 , William C. Reinhold 9 , Vinodh Rajapakse 9 , Yves Pommier 9 , Roberto Weigert 2 , W. Marston Linehan 4 and Stanley Lipkowitz 1 1 Women’s Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA 2 Laboratory of Cellular and Molecular Biology, CCR, NCI, NIH, Bethesda, MD, USA 3 Electron Microscope Laboratory, Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD, USA 4 Urologic Oncology Branch, CCR, NCI, NIH, Bethesda, MD, USA 5 CCR Collaborative Bioinformatics Resource, Leidos Biomedical Research, Inc., FNLCR, Frederick, MD, USA 6 Experimental Transplantation and Immunology Branch, CCR, NCI, NIH, Bethesda, MD, USA 7 RNA Molecular Biology Group, Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, USA 8 CCR Sequencing Facility, Leidos Biomedical Research, Inc., FNLCR, Frederick, MD, USA 9 Developmental Therapeutics Branch, CCR, NCI, NIH, Bethesda, MD, USA Correspondence to: Stanley...