A commensal strain of Staphylococcus epidermidis protects against skin neoplasia

作者：Teruaki Nakatsuji, Tiffany H. Chen, Anna M. Butcher, Lynnie Trzoss, Sang‐Jip Nam, Karina T. Shirakawa, Wei Lan Zhou, Julia Oh, Michael J. Otto, William Fenical, Richard L. Gallo · 发表于：Science Advances · 年份：2018 · DOI：10.1126/sciadv.aao4502 · 被引用次数：321 · 研究领域：Dermatology and Skin Diseases、Bacterial biofilms and quorum sensing、Plant-Microbe Interactions and Immunity

strains producing 6-HAP were found in the metagenome from multiple healthy human subjects, suggesting that the microbiome of some individuals may confer protection against skin cancer. These findings show a new role for skin commensal bacteria in host defense.