A New Fluorescent Probe Based on Aggregation Induced Emission for Selective and Quantitative Determination of Copper(II) and its Further Application to Cysteine Detection

作者：Yun‐Hui Zhao, Yueyang Luo, Han Wang, Tao Guo, Hangbin Zhou, Hai‐Long Tan, Zhihua Zhou, Yunfei Long, Zilong Tang · 发表于：ChemistrySelect · 年份：2018 · DOI：10.1002/slct.201702603 · 被引用次数：33 · 研究领域：Molecular Sensors and Ion Detection、Luminescence and Fluorescent Materials、Sulfur Compounds in Biology

Abstract A new fluorescent chemosensor 2,2′‐((1E,1′E)‐hydrazine‐1,2‐diylidenebis(methanylylidene))bis(4‐(1,2,2‐triphenylvinyl)phenol) TPESAA incorporated with salicylaldehyde azine motif was developed based on aggregation‐induced emission (AIE). The probe TPESAA was prepared from 4‐hydroxy tetraphenyl ethylene which underwent formylation followed by condensation with hydrazine hydrate. It showed ratiometric fluorescence quenching behavior to Cu 2+ , which could induce naked‐eye color changes from colorless to pale yellow. Moreover, it displayed excellent sensitivity and selectivity toward Cu 2+ without interference from other metal ions. The extent of quenching is dependent on the concentration of Cu 2+ in the range of 0.5–7.5 μM, and a remarkable detection limit (30.9 nM) can be achieved. Furthermore, the obtained Cu 2+ complex could be applied to quantitative determination of cysteine in the range of 0.2–2 μM with a good linear relationship.