Early Changes in Apparent Diffusion Coefficient for Salivary Glands during Radiotherapy for Nasopharyngeal Carcinoma Associated with Xerostomia

作者：Qing Zhang, Yumei Wei, Yuangang Qi, Baosheng Li · 发表于：Korean Journal of Radiology · 年份：2018 · DOI：10.3348/kjr.2018.19.2.328 · 被引用次数：15 · 研究领域：Head and Neck Cancer Studies、MRI in cancer diagnosis、Salivary Gland Disorders and Functions

Objective: To evaluate the early changes in the apparent diffusion coefficient (ADC) of the salivary glands during radiotherapy (RT) and their association with the degree of xerostomia at 6 months after RT in patients with nasopharyngeal carcinoma (NPC). Materials and Methods: ) were compared to the degree of xerostomia at 6 months after RT. Results: < 0.01). Conclusion: The ADCs of the salivary glands change early during RT. The differences in the ADC increase and increase rate of the parotid glands between 2 weeks after the beginning of RT and baseline were associated with the degree of xerostomia at 6 months after RT.