Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients

作者：Alice Turner, Jan Stolk, Robert Bals, Jason D. Lickliter, James Hamilton, Dawn R. Christianson, Bruce D. Given, Jonathan Burdon, Rohit Loomba, James K. Stoller, Jeffrey Teckman · 发表于：Journal of Hepatology · 年份：2018 · DOI：10.1016/j.jhep.2018.03.012 · 被引用次数：67 · 研究领域：Protease and Inhibitor Mechanisms、Protein Kinase Regulation and GTPase Signaling、Blood Coagulation and Thrombosis Mechanisms