Catalytic asymmetric inverse electron demand Diels–Alder reaction of fulvenes with azoalkenes

作者：Liang Wei, Qiao Zhu, Zhi‐Min Song, Kang Liu, Chun‐Jiang Wang · 发表于：Chemical Communications · 年份：2018 · DOI：10.1039/c7cc09896k · 被引用次数：39 · 研究领域：Cyclopropane Reaction Mechanisms、Catalytic C–H Functionalization Methods、Synthesis and Catalytic Reactions

An unprecedented copper(i)-catalyzed asymmetric inverse electron demand Diels-Alder reaction of azoalkenes with fulvenes is reported. This methodology offers a directed entry to synthesize bicyclic tetrapyridazine derivatives in good yield with exclusive regioselectivity and excellent stereoselectivity.