Serum visfatin levels in non-obese women with polycystic ovary syndrome and matched controls

作者：Jinju Kim, Young Min Choi, Min A. Hong, Min-Jeong Kim, Soo Jin Chae, Sun Mie Kim, Kyu Ri Hwang, Sang Ho Yoon, Seung‐Yup Ku, Chang Suk Suh, Seok Hyun Kim · 发表于：Obstetrics & Gynecology Science · 年份：2018 · DOI：10.5468/ogs.2018.61.2.253 · 被引用次数：25 · 研究领域：Ovarian function and disorders、Adipokines, Inflammation, and Metabolic Diseases、Regulation of Appetite and Obesity

OBJECTIVE: The purpose of the current study was to compare the circulating levels of visfatin between women with polycystic ovary syndrome (PCOS) and those without PCOS and to assess the correlations between visfatin levels and various parameters. METHODS: This case-control study recruited 74 PCOS patients and 74 age- and body mass index (BMI)-matched controls. Serum visfatin levels were evaluated using the enzyme-linked immunosorbent assay. Women with PCOS were divided into 2 subgroups based on the presence of clinical or biochemical hyperandrogenism. The possible differences in serum visfatin levels between the hyperandrogenic and non-hyperandrogenic groups were also assessed. RESULTS: =0.025). Except for HDL cholesterol levels, these correlations were also observed in controls. CONCLUSION: Visfatin levels in PCOS patients were similar to those in the controls. However, hyperandrogenic patients showed significantly higher serum visfatin levels than those of non-hyperandrogenic patients, and visfatin had a positive linear correlation with FAI in both PCOS patients and controls.