Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

作者：Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li, Rasmus Hansen, Ulf Peters, Xin Guo, Yuching Chen, Anjali Babbar, Sarah J. Firdaus, Levan Darjania, Jun Feng, Jeffrey H. Chen, Shuangwei Li, Shisheng Li, Yun Oliver Long, Carol Thach, Yuan Liu, Yuan Liu, Ata Zarieh, Tess Ely, Jeff Kucharski, Linda Kessler, Ke Yu, Ke Yu, Yi Wang, Yvonne Yao, Xiaohu Deng, Patrick P. Zarrinkar, Dirk Brehmer, Dashyant Dhanak, Matthew V. Lorenzi, Dana Hu-Lowe, Matthew P. Patricelli, Pingda Ren, Yi Liu, Yi Liu · 发表于：Cell · 年份：2018 · DOI：10.1016/j.cell.2018.01.006 · 被引用次数：1194 · 研究领域：Protein Kinase Regulation and GTPase Signaling、Ubiquitin and proteasome pathways、Peptidase Inhibition and Analysis