Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient

作者：Nam Nhut Phan, Chih‐Yang Wang, Kuan-Lun Li, Chien‐Fu Chen, Chung-Chieh Chiao, Han-Gang Yu, Pung-Ling Huang, Yen-Chang Lin · 发表于：Oncotarget · 年份：2018 · 被引用次数：106 · 研究领域：Cancer-related Molecular Pathways、Microtubule and mitosis dynamics、Cancer Cells and Metastasis

// Nam Nhut Phan 1, 2, * , Chih-Yang Wang 3, * , Kuan-Lun Li 1 , Chien-Fu Chen 4 , Chung-Chieh Chiao 4 , Han-Gang Yu 5 , Pung-Ling Huang 1, 6 and Yen-Chang Lin 1 1 Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan 2 NTT Institute of Hi-Technology, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam 3 Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan 4 School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan 5 Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV, USA 6 Department of Horticulture & Landscape Architecture, National Taiwan University, Taipei, Taiwan * These authors have contributed equally to this work Correspondence to: Pung-Ling Huang, email: pungling@ntu.edu.tw Yen-Chang Lin, email: lycnthu@gmail.com Keywords: cell cycle division-associated (CDCA) protein; breast cancer; cell cycle; prognosis; bioinformatics Received: October 16, 2017 Accepted: January 03, 2018 Published: January 09, 2018 ABSTRACT Breast cancer is a dangerous disease that results in high mortality rates for cancer patients. Many methods have been developed for the treatment and prevention of this disease. Determining the expression patterns of certain target genes in specific subtypes of breast cancer is important for developing new therapies for breast cancer. In the present study, we performed a...