Efficacy and safety of thrombopoietin receptor agonists in children with chronic immune thrombocytopenia: a meta-analysis

作者：Jian-Chun Guo, Yi Zheng, Haitao Chen, Haixia Zhou, Xianhui Huang, Li-Ping Zhong, Huaibin Zhou, Yu Huang, Danli Xie, Yongliang Lou · 发表于：Oncotarget · 年份：2017 · DOI：10.18632/oncotarget.23487 · 被引用次数：16 · 研究领域：Platelet Disorders and Treatments、Blood groups and transfusion、Heparin-Induced Thrombocytopenia and Thrombosis

// Jian-Chun Guo 1, 2, * , Yi Zheng 1, 2, * , Hai-Tao Chen 4 , Haixia Zhou 3 , Xian-Hui Huang 1, 2 , Li-Ping Zhong 1, 2 , Huai-Bin Zhou 1, 2 , Yu Huang 5 , Dan-Li Xie 1, 2 and Yong-Liang Lou 1, 2 1 Department of Microbiology and Immunology, School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China 2 China Ministry of Education Key Lab of Laboratory Medicine, Wenzhou, Zhejiang 325035, China 3 Department of Hematology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China 4 Department of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China 5 Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Key Laboratory of Hepatology, Hepatology Institute of Wenzhou Medical University, Wenzhou, Zhejiang 325025, China * These authors contributed equally to this work and should be considered co-first authors Correspondence to: Yong-Liang Lou, email: lyl@wmu.edu.cn Dan-Li Xie, email: xiedl001@wmu.edu.cn Keywords: thrombopoietin receptor agonists; immune thrombocytopenia; children; meta-analysis Received: September 30, 2017      Accepted: November 15, 2017      Published: December 19, 2017 ABSTRACT Background and Aim: Thrombopoietin receptor agonists (TPO-RAs) have been shown to be safe and effective for adults with chronic immune thrombocytopenia (ITP)...