Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression

作者：Dong-liang Chen, Yun-Xin Lu, Jiaxing Zhang, Xiao-Li Wei, Feng Wang, Zhao-Lei Zeng, Zhi-Zhong Pan, Yunfei Yuan, Feng-Hua Wang, Hélène Pelicano, Paul J. Chiao, Peng Huang, Dan Xie, Yuhong Li, Huai‐Qiang Ju, Rui‐Hua Xu · 发表于：Theranostics · 年份：2017 · DOI：10.7150/thno.20942 · 被引用次数：314 · 研究领域：Cancer-related molecular mechanisms research、RNA modifications and cancer、Circular RNAs in diseases

taken together, our findings demonstrate how UICLM induces CRC liver metastasis and may offer a novel prognostic marker and therapeutic target for this disease.