miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness

作者：Qing Zhang, Junlong Zhuang, Yongming Deng, Lin Yang, Wenmin Cao, Wei Chen, Tingsheng Lin, Xiaoyu Lv, Hang Yu, Yanshi Xue, Hongqian Guo · 发表于：Theranostics · 年份：2017 · DOI：10.7150/thno.21713 · 被引用次数：62 · 研究领域：Cancer Cells and Metastasis、Epigenetics and DNA Methylation、Bladder and Urothelial Cancer Treatments

Our results suggest that miR34a/GOLPH3 axis exert key role in CSCs involved UBC drug resistance and recurrence and warrant further development as a promising therapeutic approach in treating drug-resistant UBC.