PGE 2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

作者：Catherine A. Loynes, Jou A. Lee, Anne L. Robertson, Michael JG. Steel, Felix Ellett, Yi Feng, Bruce D. Levy, Moira K. B. Whyte, Stephen A. Renshaw · 发表于：Science Advances · 年份：2018 · DOI：10.1126/sciadv.aar8320 · 被引用次数：220 · 研究领域：Neutrophil, Myeloperoxidase and Oxidative Mechanisms、Immune Response and Inflammation、Immune cells in cancer

) in an in vivo model of inflammation resolution. This pathway may contain therapeutic targets for driving inflammation resolution in chronic inflammatory disease.