Discovery of aminocyclohexene analogues as selective and orally bioavailable hNav1.7 inhibitors for analgesia

作者：Mingxing Teng, Wentao Wu, Zhixiang Li, Guangwen Yang, Jian Qin, Yikai Wang, Zhijing Hu, Haiheng Dong, Lijuan Hou, Guoping Hu, Liang Shen, Yang Zhang, Jian Li, Shuhui Chen, Jingwei Tian, Liang Ye, Jianzhao Zhang, Hongbo Wang · 发表于：Bioorganic & Medicinal Chemistry Letters · 年份：2017 · DOI：10.1016/j.bmcl.2017.10.010 · 被引用次数：10 · 研究领域：Pain Mechanisms and Treatments、Ion channel regulation and function、Neuroscience and Neuropharmacology Research