Serum ferritin and primary lung cancer

作者：Zhongqing Chen, Bo Zhu, Chao Ou, Yuxuan Li · 发表于：Oncotarget · 年份：2017 · DOI：10.18632/oncotarget.21518 · 被引用次数：11 · 研究领域：Iron Metabolism and Disorders、Inflammatory Biomarkers in Disease Prognosis、MicroRNA in disease regulation

// Zhongqing Chen 1 , Bo Zhu 1 , Chao Ou 2 and Yuxuan Li 3 1 Department of Clinical Laboratory, Guangxi Medical University Affiliated Tumor Hospital, Nanning 530021, Guangxi Province, P.R. China 2 Experimental Research Department, Guangxi Medical University Affiliated Tumor Hospital, Nanning 530021, Guangxi Province, P.R. China 3 Department of Hepatobiliary Surgery, Guangxi Medical University Affiliated Tumor Hospital, Nanning 530021, Guangxi Province, P.R. China Correspondence to: Bo Zhu, email: profbozhu@163.com Keywords: primary lung cancer, Serum ferritin, Hemoglobin, Transferrin, Menopause Abbreviations: serum ferritin (SF); tumor-nodes-metastasis (TNM); hemoglobin (Hb); transferrin (TRF) Received: July 28, 2017      Accepted: September 04, 2017      Published: October 04, 2017 ABSTRACT Existing research yields conflicting results regarding the relation between iron deficiency and high serum ferritin (SF) levels in primary lung cancer patients. We investigated the concentrations of SF, hemoglobin (Hb) and transferrin (TRF) in 569 male primary lung cancer patients and 252 female primary lung cancer patients. We grouped the subjects according to gender, smoking status, menopausal status, pathological type, stage, and TNM stage. The levels of SF and TRF were correlated with T stage in male patients ( p<0.01 ). The levels of SF and TRF were correlated with menopausal status in female patients ( p<0.01 ). Hb was correlat...