Evaluating the prognostic value of miR-148/152 family in cancers: based on a systemic review of observational studies

作者：Fujiao Duan, Weigang Liu, Xiaoli Fu, Yajing Feng, Liping Dai, Shuli Cui, Zhenxing Yang · 发表于：Oncotarget · 年份：2017 · DOI：10.18632/oncotarget.20830 · 被引用次数：27 · 研究领域：MicroRNA in disease regulation、Ferroptosis and cancer prognosis、Circular RNAs in diseases

// Fujiao Duan 1, 2, 6 , Weigang Liu 3 , Xiaoli Fu 2 , Yajing Feng 2, 4 , Liping Dai 2, 6 , Shuli Cui 5 and Zhenxing Yang 1 1 Medical Research Office, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan, China 2 College of Public Health, Zhengzhou University, Zhengzhou, Henan, China 3 Medical Record Statistics Office, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, China 4 Department of Nosocomial Infection Management, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China 5 College of Professional Study, Northeastern University, Boston, Massachusetts, USA 6 Henan Key Laboratory of Tumor Epidemiology, Zhengzhou, Henan, China Correspondence to: Fujiao Duan, email: fjduan@yeah.net Zhenxing Yang, email: yangzhenxing59@126.com Keywords: miR-148/152 family, prognosis, cancer, systems assessment Received: July 14, 2017      Accepted: August 27, 2017      Published: September 11, 2017 ABSTRACT Background: The prognostic significance of MicroRNA-148/152 (miR-148/152) family expression in various cancers has been investigated by many studies with inconsistent results. To address this issue, we performed a meta-analysis to clarify this relationship. Materials and Methods: Eligible studies were recruited by a systematic literature search and assessed the quality of included studies based on Quality In Prognosis Studies (QUIPS) and Newcastle-Ottawa Scale (NOS). Pooled hazard ...